To provide an elastase activity inhibitor that includes a plant-derived component and is safe and excellent in effect.SOLUTION: The elastase activity inhibitor is provided that includes, as an active ingredient, (a) grape fruit extract and (b) polymethoxyflavone represented by formula [I] (In the formula, R, R, Rindependently represent a hydrogen atom or a methoxy group).SELECTED DRAWING: None【課題】植物由来の成分を含み安全でかつ効果の優れているエラスターゼ活性阻害剤を提供する。【解決手段】有効成分として、(a)ブドウ果実の抽出物及び(b)式[I]で表されるポリメトキシフラボンを含むエラスターゼ活性阻害剤:(式中、R1、R2、R3はそれぞれ独立して水素原子又はメトキシ基を表す)。【選択図】なし