PROBLEM TO BE SOLVED: To provide an antithrombotic agent including a compound having excellent TAFIa inhibitory activity as an active constituent.SOLUTION: The antithrombotic agent includes, as an active constituent: a dihydroimidazoquinoline compound represented by formula (I) wherein R denotes a hydrogen atom or a 1 to 10C alkyl group R1 denotes a hydrogen atom 1 to 10C alkyl group a 3 to 8C cycloalkyl group or the like and R2 denotes a hydrogen atom or the one represented by the structure of formula (Ic) or (Id) or its pharmaceutically allowable salt.COPYRIGHT: (C)2013,JPO&INPIT【課題】優れたTAFIa阻害活性を有する化合物を有効成分として含有する抗血栓剤を提供する。【解決手段】下記式(I){式中、Rは、水素原子又はC1-10アルキル基を示し、R1は、水素原子、C1-10アルキル基、C3-8シクロアルキル基等を示し、R2は、水素原子又は下記式Ic、Idの構造で表されるものを示す。で表されるジヒドロイミダゾキノリン化合物又はその製薬学的に許容される塩を有効成分とする抗血栓剤。【選択図】なし
