POPPY FIRZANI ARIFIN,DEASY DIAH DWI RETNO WULAN,VERONIKA YULIANI,JAMES M. SINAMBELA,RAYMOND R. TJANDRAWINATA
申请号:
US15297359
公开号:
US20170128513A1
申请日:
2016.10.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Extract and/or fraction from Cinnamomum burmanii (DLBS2411) related to its extraction method and its biological activities show activities as antiulcer by conferring mucoprotection and down-regulating H+/KT+ ATPase. Treatment with DLBS2411 decreases the H+/K+ ATPase mRNA level in HEK 293 and gastric parietal cells. In addition, DLBS2411 inhibits activity of H+/K+ ATPase gastric enzyme wherein pH influences this inhibition mechanism. DLBS2411 also has characteristic as antioxidant which is shown by the increase of reducing power as the given dosage increases.