Maria-Clemencia Hernandez;Andrew Thomas;Matthew C. Lucas
发明人:
Maria-Clemencia Hernandez,Matthew C. Lucas,Andrew Thomas
申请号：
US13287149
公开号：
US20120115844A1
申请日:
2011.11.02
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is concerned with novel triazole compounds of formula (I)wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.
