triazole compounds iii

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

ANDREW THOMAS

申请号：

BR112013014362

公开号：

BR112013014362A2

申请日:

2011.12.07

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The present invention is concerned with novel 1,2,3-triazole-imidazole compounds of formula (I) wherein X, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A alpha5 receptor. Further the present invention provides a method for the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as therapeutic agents.

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