COMPOSÉS N-(PHÉNYLSULFONYL)BENZAMIDIQUES ET COMPOSÉS APPARENTÉS EN TANT QU'INHIBITEURS DE BCL-2

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专利权人:

The Regents of The University of Michigan

发明人:

申请号：

EP19184604.7

公开号：

EP3569601A3

申请日:

2017.08.04

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present disclosure provides compounds having Formula I-A:and the pharmaceutically acceptable salts and solvates thereof, wherein A, X1, X2, X3 R1a, R1b, E, and --- are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I-A for use to treat a disease, disorder, or condition responsive to Bcl-2 protein inhibition such as cancer.

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