HWANG, SANG YOUN,HUH, YONG HO,KIM, JIN YOUNG,HONG, SUNG HEE,CHOI, IN YOUNG,JUNG, SUNG YOUB,KWON, SE CHANG,KIM, DAE JIN,KIM, HYUN UK,JANG, MYUNG HYUN,KIM, SEUNG SU,黃祥淵,許容豪,金真英,洪性熙,崔仁榮,鄭聖燁,權世昌,金大振,金賢煜,張明賢,KIM, SEUNG
申请号:
HK15112526.1
公开号:
HK1211944A
申请日:
2015.12.18
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention relates to an insulin analog that has a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin, a conjugate prepared by linking the insulin analog and a carrier, a long-acting formulation including the conjugate, and a method for preparing the conjugate.