HWANG, Sang Youn,HUH, Yong Ho,KIM, Jin Young,HONG, Sung Hee,CHOI, In Young,JUNG, Sung Youb,KWON, Se Chang,KIM, Dae Jin,KIM, Hyun Uk,JANG, Myung Hyun,KIM, Seung Su
申请号:
DK14757629
公开号:
DK2963056T3
申请日:
2014.02.26
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The present invention relates to an insulin analog that has a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin, a conjugate prepared by linking the insulin analog and a carrier, a long-acting formulation including the conjugate, and a method for preparing the conjugate.