Sang Youn HWANG,Yong Ho HUH,Jin Young KIM,Sung Hee HONG,In Young CHOI,Sung Youb JUNG,Se Chang KWON,Dae Jin KIM,Hyun Uk KIM,Myung Hyun JANG,Seung Su KIM
申请号：
US14769495
公开号：
US20160008483A1
申请日:
2014.02.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to an insulin analog that has a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin, a conjugate prepared by linking the insulin analog and a carrier, a long-acting formulation including the conjugate, and a method for preparing the conjugate.
