HWANG, SANG YOUN,HUH, YONG HO,KIM, JIN YOUNG,HONG, SUNG HEE,CHOI, IN YOUNG,JUNG, SUNG YOUB,KWON, SE CHANG,KIM, DAE JIN,KIM, HYUN UK,JANG, MYUNG HYUN,KIM, SEUNG SU
申请号:
SG11201506095T
公开号:
SG11201506095TA
申请日:
2014.02.26
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention relates to an insulin analog that has a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin, a conjugate prepared by linking the insulin analog and a carrier, a long-acting formulation including the conjugate, and a method for preparing the conjugate.