Sang Youn Hwang,Yong Ho Huh,Jin Young Kim,Sung Hee Hong,In Young Choi,Sung Youb Jung,Se Chang Kwon,Dae Jin Kim,Hyun Uk Kim,Myung Hyun Jang,Seung Su Kim
申请号:
US15983923
公开号:
US20180256731A1
申请日:
2018.05.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An insulin analog has a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin. A conjugate is prepared by linking the insulin analog and a carrier. A long-acting formulation includes the conjugate.