A method of brewing a litchi (lychee) nutritive wine comprises (i) selection and processing of raw materials: clean fresh litchi and dry in air, peel off the skin, denucleate the litchi and cut up pulp; husk selected walnut and remove the impurities; remove impurities of sesame and sorghum; (2) fermentation: mix the processed sorghum, litchi, sesame and walnut prepared in step (1); place them into a fermentation cylinder and mix them with notopterygium; ferment the mixture at a temperature of 20-35oC for 60-80 days; after the fermentation process, remove the wine tears; (3) ageing: place the brewed wine in step (2) into a ceramic wine reservoir and age the mixture at a temperature of 10-15oC for 6-12 months; (4) blending: blend the aged brewed wine from step (3) with a base liquor in appropriate proportions; (5) filtering and filling: degerming the blended wine with a millipore filtration (pore size of the membrane being 0.10-0.22µm); conducting the filling process in an aseptic environment to obtain the nutritive litchi wine. Preferably the base liquor is a distilled base liquor made up of rice, sticky rice, corn, wheat and sorghum, wherein the volume ratio of the ageing brewed wine and base liquor is preferably 1:4-7:3. Preferably the mass percent of the raw materials are 40-70% sorghum, 20-40% litchi, 5-10% sesame and 5-10% walnut. Preferably the notopterygium accounts for 4-8% of the total mass of raw materials.