PROBLEM TO BE SOLVED: To provide a composition for prevention of cancers, which suppresses at least two stages in a multistage carcinogenesis process by carcinogen and which has high safeness.SOLUTION: The composition includes, as an active ingredient, Actinidia arguta juice or a high polarity organic solvent extract of Actinidia arguta juice, having an inhibition effect on at least two activities in multistage carcinogenesis activities by carcinogen, particularly, on an initiation activity and a promotion activity. Medicines, foods and fodders including the composition are disclosed, having a cancer preventing effect on a subject requiring cancer prevention.COPYRIGHT: (C)2013,JPO&INPIT【課題】発癌性物質による多段階発癌過程の少なくとも2つ以上の過程を抑制し、かつ安全性が高い癌予防用の組成物を提供する。【解決手段】発癌性物質による多段階発癌活性の2以上の活性、特にイニシエーション活性及びプロモーション活性に対して阻害作用を有する、サルナシ果汁又はサルナシ果汁の高極性有機溶媒抽出物を有効成分とする組成物、及びそれを含有する、癌の予防が必要な対象における発癌予防効果を有する医薬、食品又は飼料。【選択図】図1
