PROBLEM TO BE SOLVED: To provide a component derived from wakame seaweed which is novel as an active ingredient of AMPK activity-promoting composition.SOLUTION: (1) AMPK activity-promoting composition has an extract, which is obtained by hydrolyzing wakame seaweed to which alginic acid decomposition treatment is performed, separating and recovering an insoluble fraction of obtained hydrolysate, and extracting the recovered insoluble fraction by organic solvent, as an active ingredient. (2) AMPK activity-promoting composition described in the (1) in which the organic solvent is hydrocarbon-based solvent or lower alcohol. (3) AMPK activity-promoting composition has peptide derived from wakame seaweed as an active ingredient.SELECTED DRAWING: None【課題】わかめ由来の成分であって、AMPK活性促進用組成物の有効成分として新規なものを提供する。【解決手段】(1)アルギン酸の分解処理をしたわかめを加水分解し、得られた加水分解物の不溶性画分を分離して回収し、当該回収した不溶性画分を有機溶媒で抽出して得られた抽出物を有効成分とするAMPK活性促進用組成物。(2)前記有機溶媒が、炭化水素系溶媒又は低級アルコールである前記(1)に記載のAMPK活性促進用組成物。(3)わかめ由来のペプチドを有効成分とするAMPK活性促進用組成物。【選択図】 なし