BRADNER, James,BUCKLEY, Dennis,ISHOEY ROSENBAUM, Mette,WINTER, Georg
申请号：
EP17873287
公开号：
EP3544957A4
申请日:
2017.11.22
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
or an enantiomer, diastereomer, or stereoisomer thereof, or pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, which act as protein degradation inducing moieties for protein kinases. The present application also relates to methods for the targeted degradation of one or more protein kinases through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to one or more protein kinases which can be utilized in the treatment of disorders modulated by protein kinases.
