Mickle, Travis,Guenther, Sven,Mickle, Christal,Chi, Guochen,Kanski, Jaroslaw,Martin, Andrea K.,Bera, Bindu
申请号：
AU2010266205
公开号：
AU2010266205A1
申请日:
2010.07.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.
