BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

• 收藏
• 分享

专利权人:

INC.;KEMPHARM

发明人:

申请号：

IL21709611

公开号：

IL217096D0

申请日:

2011.12.20

申请国别(地区):

IL

年份:

2012

代理人:

摘要：

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/