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Taxane polymer conjugates
专利权人:
日本化薬株式会社
发明人:
北川 正行,石川 恵三,恩田 健
申请号:
JP2008507452
公开号:
JP5249016B2
申请日:
2007.03.22
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
[Problems] To provide a novel taxane derivative which can release the medicinal substance in a bioenzyme-independent manner, is expected to have an effective therapeutic efficacy, and has a water-solubility. [Means for Solving Problems] Disclosed is a polymer conjugate of a taxane, which comprises a polymer having a polyethylene glycol moiety and two or more succinic acid monoamide moieties and a taxane, wherein a carboxylate group in the polymer and an alcoholic hydroxyl group in the taxane are bound to each other via an ester bonding.
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