KALLUS, CHRISTOPHER,BROENSTRUP, MARK,CZECHTIZKY, WERNGARD,EVERS, ANDREAS,FOLLMANN, MARKUS,HALLAND, NIS,SCHREUDER, HERMAN
申请号：
ES07856207
公开号：
ES2537093T3
申请日:
2007.11.22
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Compound of formula I ** Formula ** and / or a stereoisomeric form of the compound of formula I and / or mixtures of these forms in any ratio, and / or a physiologically compatible salt of the compound of formula I, in which X represents - SO2-, R1 represents 1) hydrogen atom, 2) -alkyl- (C1-C6), 3) -alkylene- (C0-C4) -cycloalkyl- (C3-C12) or 4) -alkylene- (C1-C6 ) -aryl- (C6-C14), R2 represents the remainder of formula II - (A1) m-A2 (II), in which m means the integer zero or 1, A1 represents 1) - (CH2) n- , where n means the integer zero, 1, 2 or 3, 2) -NH- (CH2) n-, where n means the integer zero, 1, 2 or 3, 3) -NH (alkyl - (C1-C6)) - (CH2) n-, where n means the integer zero, 1, 2 or 3, 4) -NH (cycloalkyl- (C3-C6)) - (CH2) n-, where n means the integer zero, 1, 2 or 3, 5) -O- (CH2) n-, where n means the integer zero, 1, 2 or 3 or 6) - (CH2) n -SOx-, in which n means the integer zero, 1, 2 or 3 and x means the number e ntero zero, 1 or 2, A2 represents 1) Het, Het being understood as a 4 to 15-membered heterocyclic ring system with 4 to 15 ring atoms, which are found in one, two or three ring systems linked together and containing one, two, three or four heteroatoms the same or different from the oxygen, nitrogen or sulfur series and is not independently substituted or substituted with each other once, twice or three times with a -alkyl- (C1-C3), halogen, - NH2, -CF3 or -O-CF3, 2) -alkylene- (C0-C6) -NH2, 3) -alkylene- (C1-C6) -NH-C (>； = NH) -NH2, 4) -alkylene- (C1-C6) -NH-C (>； = NH) -alkyl- (C1-C4), 5) -alkylene- (C0-C4) -O-NH-C (>； = NH) -NH2, 6) - alkylene- (C0-C4) -NH-C (O) -alkyl- (C1-C6), 7) -alkylene- (C1-C6) -NH-C (O) -O-alkylene- (C1-C4) -aryl, in which aryl is unsubstituted or substituted with - NH2 or is substituted with -NH2 and once, twice or three times with R15, 8) -cycloalkyl- (C3-C8) -NH2 or 9) -alkylene- ( C0-C4) -aryl- (C6-C14), in which aryl is unsubstituted or substituted with -NH2 or is substituted with -NH2 and once, twice or three t
