BOURKE DAVID GERARD,BURNS CHRISTOPHER JOHN,CUZZUPE ANTHONY NICHOLAS,FEUTRILL JOHN THOMAS,KLING MARCEL ROBERT,NERO TRACY LEAH,KL
申请号：
PL08849455
公开号：
PL2215094T3
申请日:
2008.11.14
申请国别(地区):
PL
年份:
2016
代理人:
摘要：
The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants； hyperproliferative diseases including cancer and myeloproliferative diseases； viral diseases； metabolic diseases； and vascular diseases.
