BOURKE, David Gerard,BU, Xianyong,BURNS, Christopher John,CUZZUPE, Anthony Nicholas,FEUTRILL, John Thomas,NERO, Tracy Leah,BLANNIN, Beata Maria,ZENG, Jun,GAYNOR, Shaun Patrick
申请号：
AU2013263739
公开号：
AU2013263739A1
申请日:
2013.11.27
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2013263739A120140116.pdf#####ABSTRACT The present invention relates to thiopyrimidine-based compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are 5 selective for JAKI, JAK2 or JAK3 kinases and combinations thereof such as JAKI and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants hyperproliferative diseases including cancer and myeloproliferative diseases viral diseases metabolic diseases and vascular diseases. 10 4895540_1 (GHMatters) P72623.AU.1
