Blannin, Beata Maria,Feutrill, John Thomas,Nero, Tracy Leah,Cuzzupe, Anthony Nicholas,Bu, Xianyong,Zeng, Jun,Bourke, David Gerard,Gaynor, Shaun Patrick,Burns, Christopher John
申请号：
AU2008210266
公开号：
AU2008210266B2
申请日:
2008.01.31
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to thiopyrimidine-based compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2 or JAK3 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants； hyperproliferative diseases including cancer and myeloproliferative diseases； viral diseases； metabolic diseases and vascular diseases.
