David G. Bourke,Christopher J. Burns,Anthony N. Cuzzupe,John T. Feutrill,Marcel R. Kling,Tracy L. Nero
申请号：
US14278394
公开号：
US09499560B2
申请日:
2014.05.15
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants； hyperproliferative diseases including cancer and myeloproliferative diseases； viral diseases； metabolic diseases； and vascular diseases.
