The compound of the bright Department Off whats As Alkaline of this Hair or acid plus the logical formula (I) at Which forms and hydrate or molten Elixirs solvate forms:Wherein X1,X2,X3And X4Independence on the spot indicates Hydrogen Huo Halogen elements atoms or C1 each other- C6Alkyl, C3- C7- Ring alkyl, C3- C7- Ring alkyl-C1- C3Stretch alkyl, C1- C6Fluoroalkyl, C1- C6Alkoxy, C1- C6Fluoroalkyloxy, cyano, C (O) NR1R2, nitro, NR1R2,C1- C6Sulfanyl ,-S (O)-C1- C6Alkyl ,-S (O) 2- C1- C6Alkyl, SO2NR1R2,NR3COR4,NR3SO2R5Or aryl, The aryl Visual Qing Condition The replaceW indicates the Chou He Twin Ring Ji Mission of following formula:Its The is by 1,2,3 or 4 Wei Key Knot what nitrogen-atomsA indicates to include 5- to 7- STAFF Miscellaneous Rings of 1 to the 3 Ge Election from O, S and N Miscellaneous atomsThe carbon atom Visual Qing Condition The of A replaceThe nitrogen-atoms Visual Qing Condition The of A replaceThe whats such as n 1,2 or 3Y indicates Visual Qing Condition The substitution Miscellaneous aryl.Qi System Prepare methods of the bright Yi You Off of this Hair and control Treatment purposes.本發明係關於為鹼或酸加成鹽形式以及水合物或溶劑合物形式之通式(I)之化合物:其中X1、X2、X3及X4彼此獨立地表示氫或鹵素原子或C1-C6-烷基、C3-C7-環烷基、C3-C7-環烷基-C1-C3-伸烷基、C1-C6-氟烷基、C1-C6-烷氧基、C1-C6-氟烷氧基、氰基、C(O)NR1R2、硝基、NR1R2、C1-C6-硫烷基、-S(O)-C1-C6-烷基、-S(O)2-C1-C6-烷基、SO2NR1R2、NR3COR4、NR3SO2R5或芳基,該芳基視情況經取代;W表示下式之稠合雙環基團:其經由1、2、3或4位鍵結於氮原子;A表示包含1至3個選自O、S及N之雜原子的5-至7-員雜環;A之碳原子視情況經取代;A之氮原子視情況經取代;n等於1、2或3;Y表示視情況經取代之雜芳基。本發明亦有關其製備方法及治療用途。
