LEONARD, KRISTI A.,BARBAY, KENT,EDWARDS, JAMES P.,KREUTTER, KEVIN D.,KUMMER, DAVID A.,MAHAROOF, UMAR,NISHIMURA, RACHEL,URBANSKI, MAUD,VENKATESAN, HARIHARAN,WANG, AIHUA,WOLIN, RONALD L.,WOODS, CRAIG R.
申请号:
CA2927153
公开号:
CA2927153A1
申请日:
2013.10.15
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention comprises compounds of Formula (I). wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.