LEONARD, Kristi A.,BARBAY, Kent,EDWARDS, James P.,KREUTTER, Kevin D.,KUMMER, David A.,MAHAROOF, Umar,NISHIMURA, Rachel,URBANSKI, Maud,VENKATESAN, Hariharan,WANG, Aihua,WOLIN, Ronald L.,WOODS, Craig R.
申请号:
ES13786779
公开号:
ES2770676T3
申请日:
2013.10.15
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
The present invention comprises compounds of Formula (I). wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.