METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

LEONARD, KRISTI, A.,BARBAY, KENT,EDWARDS, JAMES, P.,KREUTTER, KEVIN, D.,KUMMER, DAVID, A.,MAHAROOF, UMAR,NISHIMURA, RACHEL,URBANSKI, MAUD,VENKATESAN, HARIHARAN,WANG, AIHUA,WOLIN, RONALD, L.,WOODS, CRA

申请号：

PH12015500817

公开号：

PH12015500817A1

申请日:

2015.04.14

申请国别(地区):

PH

年份:

2015

代理人:

摘要：

The present invention comprises compounds of Formula (I), wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/