LOWMAN, HENRY BERNARD,DESNOYERS, LUC ROLAND,LIU, SHOUCHUN,WEST, JAMES WILLIAM,SAGERT, JASON GARY,VASILJEVA, OLGA,MENENDEZ, ELIZABETH-EDNA MARY
申请号:
HK15105286.5
公开号:
HK1204581A
申请日:
2015.06.03
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.