Lowman, Henry Bernard,Desnoyers, Luc Roland,West, James William,Sagert, Jason Gary,Vasiljeva, Olga,Menendez, Elizabeth-Edna Mary,Liu, Shouchun
申请号:
AU2018203262
公开号:
AU2018203262A1
申请日:
2018.05.10
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018203262A120180531.pdf#####ABSTRACT The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti- EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.