Henry Bernard Lowman,Luc Roland Desnoyers,Shouchun Liu,James William West,Jason Gary Sagert,Olga Vasiljeva,Elizabeth-Edna Mary Menendez
申请号：
US15381972
公开号：
US09889211B2
申请日:
2016.12.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
