Lowman, Henry Bernard,Desnoyers, Luc Roland,Liu, Shouchun,West, James William,Sagert, Jason Gary,Vasiljeva, Olga,Menendez, Elizabeth-Edna Mary
申请号:
NZ72972513
公开号:
NZ729725A
申请日:
2013.04.26
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti- EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.