PROBLEM TO BE SOLVED: To provide a method for producing a pancreatic tumor development-inhibiting composition with high physiological activity, and high pancreatic tumor development-inhibiting effect when ingesting as a food.SOLUTION: The invention relates to a method for producing a pancreatic tumor development-inhibiting composition comprising: polishing unpolished rice in a rice-polishing machine until 96% or more of a rice polishing rate and hydrating this polished rice making a hydrated mixture of rice bran and a calcium compound in a mixer separately mixing and steaming the hydrated polished rice and the hydrated mixture, and inoculating seed aspergillus into a culture bed so as to germinate stirring a substrate to radiate heat generated with fermentation, and maintaining in a suitable temperature drying a matured koji until 4% or less of water content in a temperature of goods of the substrate and powdering in a condition where enzyme activity is maintained.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】生理活性が高く、食品として摂取するとき、膵腫瘍の発生を抑制する効果の高い膵腫瘍発症抑制組成物の製造方法の提供。【解決手段】玄米を精米機で精米歩合96%以上に搗精し、この搗削玄米に含水させる工程と、別に混合機で米糠とカルシウム化合物との加水混合体を作る工程と、前記含水させた搗削玄米と加水混合体とを混合して蒸し、種麹菌を接種して培養床で発芽させる工程と、発酵に伴い基質を撹拌して放熱させ、適温に維持させる工程とを有し、熟成した麹を基質の品温で含有水分4%以下に乾燥させ、酵素の活性を維持した状態で粉末とする膵腫瘍発症抑制組成物の製造方法。【選択図】なし
