The present invention relates to an external preparation for skin containing an extract obtained from leaves, roots and roots as an active ingredient. The external preparation for skin according to the present invention is excellent in skin whitening, wrinkle improvement and moisturizing effect, and is excellent in the treatment of atopic diseases The present invention provides an external preparation for skin containing a cucurbitan extract which exerts an effect.본 발명은 꾸지뽕잎, 줄기 및 뿌리로부터 얻은 추출액을 활성성분으로 함유하는 피부외용제로써, 상기 본 발명에 따른 피부외용제는 피부미백, 주름개선 및 보습효과가 우수하면서, 아토피 질환의 치료에도 탁월한 효과를 발휘하는 꾸지뽕 추출물을 함유하는 피부외용제를 제공한다.