1. This report deals with alternative Amida derivatives for dual pharmacological activities of sigma receptor (s) and opiate receptor (m), the preparation process of these compounds, the synthesis of drugs containing these compounds and their use in treatment, especially for pain treatment. 1. Claim 1: a general formula compound (1),M is 1 or 2； n is 0 or 2； P is 0 or 1 or 2； W is nitrogen or carbon； X is a link, - C (r739)； r739；This is life, this is life, this is life.R739 selected or1 83099 from halogen；C₁₋₆-substituted or unsubstituted alkyl, C₂₋₆-substituted or unsubstituted alkenyl and C₂₋₆-substituted or unsubstituted alkynyl； Rˣ is selected from hydrogen, halogen, C o-substituted or unsubstituted alkyl, C₂₋₆-substituted or unsubstituted alkenyl, and C₂₋₆-substituted or unsubstituted alkynyl； R¹⁵ is selected from hydrogen, C o substituted or unsubstituted alkyl, C₂₋₆ substituted or unsubstituted alkenyl and C₂₋₆ substituted or unsubstituted alkynyl； R¹ is selected from substituted or unsubstituted C₁₋₆ alkyl, substituted or unsubstituted C₂₋₆ alkenyl, substituted or unsubstituted C₂₋₆ alkynyl,There are no substituted or unsubstituted cyclopentadiene compounds, substituted or unsubstituted cyclopentadiene, and substituted or unsubstituted non cyclopentadiene； in this case, cyclopentadiene or non cyclopentadiene at R1,If the substitute is replaced by one or more substitutes selected from halogen-r1,-Or1,-No.8322；-1 numberNR C (O) R-NR S (O) R-S (O) NR R-NR C (O) NR R-SR1,S (O) RS (O) R-CN haloalquilo haloalcoxi -C (O) OR-C (O) NR R-Nr.1 (o) 8322； Nr.1 R1 and C (ch83323) 8322； or1；In addition, bicycles or fragrance free heterosexuals in R1,If it is replaced, it can also be replaced by other formulas (2) or = O； in these formulas, the tar, aluminum or asphalt of R1,If replaced, by one or more alternatives selected from - or1,1. Halogen-cn, halogeo, haloalcoxi-sr1-s (o) R1 Y-S (o) c8322； R1；There R1,R¹¹ and R¹¹ are independently selected from hydrogen, unsubstitut
