CORBIN JOHN,WHITE MARK LESLIE,WATSON SUSAN R.,BHASKAR VINAY
申请号:
NZ59871310
公开号:
NZ598713A
申请日:
2010.09.25
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is an antibody that binds to (i) insulin receptor or (ii) a complex comprising insulin and insulin receptor or both (i) and (ii), with an equilibrium dissociation constant KD of 10-5M or less that is capable of weakening the binding affinity between insulin and insulin receptor by at least 3-fold, optionally up to 1000-fold