JAKOBSEN, BENT KARSTEN,LI, YI,DUNN, STEVEN MARK,MOLLOY, PETER EAMON
申请号：
CA2602463
公开号：
CA2602463C
申请日:
2006.03.29
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides TCRs having an affinity (KD) of less than orequal to l~M, and/or an off-rate (koff) of 1x10-3 S-1 or slower, for theSLYNTVATL-HLA- A* 0201 complex PROVIDED THAT when the said TCR is presented bycell and comprises SEQ ID NOs: 1 and 2, the cell is not a native T cell. SuchTCRs are useful, either alone or associated with a therapeutic agent, fortargeting HIV infected cells presenting that complex.
