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ПОТЕНЦИАЛ КАЛЕБИНА А В КАЧЕСТВЕ СРЕДСТВА ПРОТИВ ОЖИРЕНИЯ
专利权人:
МАДЖИД Мухаммед (US)
发明人:
МАДЖИД Мухаммед (US),ПАНДЕЙ Анджали (IN)
申请号:
RU2013137221/15
公开号:
RU2013137221A
申请日:
2012.01.10
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method for inhibiting adipogenesis, which includes a step in which adipocytes are contacted with an effective amount kalebina A.2. A method of inhibiting the expression of leptin in adipocytes, which includes a step in which adipocytes are contacted with an effective amount kalebina A.3. A method of inhibiting the expression of adiponectin in adipocytes, which includes a step in which adipocytes are contacted with an effective amount kalebina A.4. A method of inhibiting obesity-induced proinflammatory cytokines synthesis in adipocytes, which includes a step in which adipocytes are contacted with an effective amount kalebina A.5. A method according to claim 4, wherein the proinflammatory cytokine is tumor necrosis factor α (TNF-α) .6. A method according to claim 4, wherein the proinflammatory cytokine is an interleukin-6 (IL-6) .7. A method according to any one of claims 1-4, wherein adipocytes are cheloveka.8 adipocytes. A method for reducing obesity caused by systemic expression of proinflammatory cytokines, which includes the step of administering an effective amount kalebina A patient in this nuzhdaetsya.9. The method of claim 8, wherein the proinflammatory cytokine is tumor necrosis factor α (TNF-α) .10. The method of claim 8, wherein the proinflammatory cytokine is an interleukin-6 (IL-6) .11. The method of claim 8, wherein the proinflammatory cytokine is interleukin-1β (IL-1β) .12. A method of control of obesity, which comprises the step of administering an effective amount kalebina A patient in this nuzhdaetsya.13. A method according to claim 8 or 12, wherein the patient is a mlekopitayuschee.14. A method according to claim 8 or 12, wherein the patient Representat1. Способ ингибирования адипогенеза, который включает стадию, в ходе которой адипоциты приводят в контакт с эффективным количеством калебина A.2. Способ ингибирования экспрессии лептина в адипоцитах, который включает стадию, в ходе которой адипоциты приводят в контакт с эффективным количеством к
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