THOMAS E. RAWSON,JOSEPH P. LYSSIKATOS,BING-YAN ZHU,PAUL GIBBONS,EMILY HANAN,WENDY LIU,STEVEN R. MAGNUSON,ROHAN MENDONCA,RICHARD PASTOR,MICHAEL SIU,MARK E. ZAK,AIHE ZHOU,CHRISTOPHER HURLEY
申请号:
PT10794815
公开号:
PT2448941T
申请日:
2010.07.02
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.