GIBBONS Paul,HANAN Emily,LIU Wendy,LYSSIKATOS Joseph P.,MAGNUSON Steven R.,MENDONCA Rohan,PASTOR Richard,RAWSON Thomas E.,SIU Michael,ZAK Mark E.,ZHOU Aihe,ZHU Bing-Yan,HURLEY Christopher,PASTO
申请号:
SI201031625
公开号:
SI2448941T1
申请日:
2010.07.02
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.