GIBBONS PAUL A,HANAN EMILY,LIU WENDY,LYSSIKATOS JOSEPH P,MAGNUSON STEVEN R,MENDONCA ROHAN,PASTOR RICHARD D,RAWSON THOMAS E,SIU MICHAEL,ZAK MARK E,ZHOU AIHE,ZHU BING-YAN
申请号:
ZA201200490
公开号:
ZA201200490B
申请日:
2012.01.20
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.