Gibbons, Paul,Hanan, Emily,Liu, Wendy,Lyssikatos, Joseph P.,Magnuson, Steven R.,Mendonca, Rohan,Pastor, Richard,Rawson, Thomas E.,Siu, Michael,Zak, Mark E.,Zhou, Aihe,Zhu, Bing-Yan,Hurley, Christopher,Pastor,
申请号：
HRP20180157
公开号：
HRP20180157T1
申请日:
2018.01.26
申请国别(地区):
HR
年份:
2018
代理人:
摘要：
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.
