GIBBONS, PAUL,HANAN, EMILY,LIU, WENDY,LYSSIKATOS, JOSEPH P.,MAGNUSON, STEVEN R.,MENDONCA, ROHAN,PASTOR, RICHARD,RAWSON, THOMAS E.,SIU, MICHAEL,ZAK, MARK E.,ZHOU, AIHE,ZHU, BING-YAN,HURLEY, CHRISTOPHER
申请号:
PL10794815
公开号:
PL2448941T3
申请日:
2010.07.02
申请国别(地区):
PL
年份:
2018
代理人:
摘要:
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.