POLYPEPTIDES TARGETING HIV FUSION

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专利权人:

发明人:

KRYSTAL MARK R,WENSEL DAVID L,DAVIS JONATHAN

申请号：

IN201717037580

公开号：

IN201717037580A

申请日:

2017.10.24

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The invention is directed to polypeptides comprising a CD4 binding moiety a gp41 binding moiety a HIV fusion peptide inhibitor moiety and combinations thereof. More specifically the present invention relates to polypeptides comprising a fibronectin based scaffold domain protein that binds CD4 a fibronectin based scaffold domain protein that binds the N17 domain of gp41 and a HIV fusion peptide inhibitor or combinations thereof. The invention also relates to the use of the innovative proteins in therapeutic applications to treat HIV.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/