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Polypeptides Targeting HIV Fusion
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
Mark R. KRYSTAL,David L. WENSEL,Jonathan DAVIS
申请号:
US15568830
公开号:
US20180111980A1
申请日:
2016.04.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention is directed to polypeptides comprising a CD4 binding moiety, a gp41 binding moiety, a HIV fusion peptide inhibitor moiety and combinations thereof. More specifically, the present invention relates to polypeptides comprising a fibronectin-based scaffold domain protein that binds CD4, a fibronectin-based scaffold domain protein that binds the N17 domain of gp41, and a HIV fusion peptide inhibitor or combinations thereof. The invention also relates to the use of the innovative proteins in therapeutic applications to treat HIV.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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