Patrick M. Hughes,Orest Olejnik,Scott M. Whitcup,James A. Burke,Hughes, Patrick M.,Olejnik, Orest,Whitcup, Scott M.,Burke, James A.
申请号：
US13367070
公开号：
US20120142652A1
申请日:
2012.02.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.
