Patrick M. Hughes,Orest Olejnik,Scott M. Whitcup,James A. Burke
申请号：
US13857707
公开号：
US09572859B2
申请日:
2013.04.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.
