Burke, James A.,Olejnik, Orest,Hughes, Patrick M.,Whitcup, Scott M.
申请号：
AU2013200020
公开号：
AU2013200020A1
申请日:
2013.01.03
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013200020A120130124.pdf#####C:\NRPortbl\DCC\TXS\31654731. DOC-3/09/2010 COMPOSITIONS FOR LOCALIZED THERAPY OF THE EYE, COMPRISING PREFERABLY TRIAMCINOLONE ACETONIDE AND HYALURONIC ACID Abstract 5 Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that 10 facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, 15 and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.
