PROBLEM TO BE SOLVED: To provide a Maillard reaction inhibitor that inhibits the Maillard reaction of a protein and has an action of inhibiting the production of an advanced glycation end product, such as pentosidine or carboxymethyl lysine； a bone strength improver that makes use of the efficacy of the Maillard reaction inhibitor, serving as means of its administration； a bone quality improving agent； and an agent for preventing or ameliorating skin aging.SOLUTION: According to the present invention, there are provided a bone strength improver, bone quality improving agent, skin aging prevention or amelioration agent, Maillard reaction inhibitor, advanced glycation end product formation inhibitor, pentosidine production inhibitor, or carboxymethyl lysine production inhibitor, which contain a cocoa (Theobroma cacao) as an effective ingredient.SELECTED DRAWING: None【課題】タンパク質のメイラード反応を抑制し、ペントシジン、カルボキシメチルリジンなどの終末糖化産物の生成を阻害する作用を有する、メイラード反応抑制剤、並びに前記メイラード反応抑制剤の効能を生かした、その投与の手段としての骨強度改善剤、骨質改善剤、及び皮膚老化予防若しくは改善剤を提供する。【解決手段】カカオ（Theobromacacao）抽出物を有効成分とする、骨強度改善剤、骨質改善剤、皮膚老化予防若しくは改善剤、メイラード反応抑制剤、終末糖化産物生成阻害剤、ペントシジン生成阻害剤、又はカルボキシメチルリジン生成阻害剤。【選択図】なし
