An object of the invention is to provide a safe, novel beverage which when taken daily is effective in the prevention and treatment of osteoporosis, bone fracture, rheumatism, arthritis, and other bone diseases. The beverage contains more than 0.8mg/100ml and not more than 150mg/100ml of angiogenin and/or an angiogenin degradation product, and also contains a cystatin and/or a cystatin degradation product in a mass ratio of 0.006 to 1.7 relative to the angiogenin and/or angiogenin degradation product. When ingested, this type of beverage can strengthen bones, and is effective in the prevention and treatment of various bone diseases, particularly osteoporosis, bone fracture, rheumatism and arthritis.本發明之課題為安全且藉由日常攝取,對於骨質疏鬆症、骨折、風濕病、關節炎等各種骨疾病之預防或治療為有用的新穎飲料。係一種飲料,其血管生成素及/或血管生成素分解物之含量超過0.8mg/100ml且為150mg/100ml以下,且胱抑素及/或胱抑素分解物之含量,相對於血管生成素及/或血管生成素分解物之質量比為0.006~1.7之範圍。藉由攝取如此的飲料,能夠強化骨骼,特別是對於骨質疏鬆症、骨折、風濕病、關節炎等各種骨疾病之預防及治療有效。
