INHIBITEURS DE PROTEASE POLY-PEGYLEE

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专利权人:

DYAX CORP.

发明人:

申请号：

EP04786615.7

公开号：

EP1663281B1

申请日:

2004.08.30

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease； and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.

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中国工程科技知识中心

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http://www.ckcest.cn/home/